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Plasma chemical driven biomedical applications with a radio frequency driven atmospheric pressure plasma jet

dc.contributor.authorChoi, Myeong Yeol, author
dc.contributor.authorCollins, George J., advisor
dc.contributor.authorHendrickson, Dean A., committee member
dc.contributor.authorNotaros, Branislav, committee member
dc.contributor.authorWatanabe, Masahiro, committee member
dc.date.accessioned2007-01-03T08:26:19Z
dc.date.available2013-12-10T08:10:42Z
dc.date.issued2012
dc.description.abstractWe present radio frequency driven atmospheric pressure plasma jet for various biomedical applications such as tissue removal, bacterial sterilization, and tooth whitening. Two different types of plasma assisted electrosurgery, remote electrode plasma jet and plasma jet surrounding monopolar electrosurgical electrode, were employed to enhance tissue removal in terms of less heat damage on contiguous tissue and fast removal rate. Chlorine based chemical (CHxClx) additives in argon plasma jet enhanced tissue removal rate, proportional to the Cl radical density in the plasma jet. Pulsed RF provided another knob to control the removal profile, heat damage, and removal rate. Hydrogen peroxide (H2O2) additive provided abundant OH generation in the helium plasma jet. It not only enhanced tissue removal rate but also reduced heat damage on the contiguous tissue. The tissue removal mechanism of helium-H2O2 plasma is explained based on the FTIR measurement of the tissue samples, and optical emission and absorption spectra. Hydrogen peroxide addition to argon plasma jet was employed for bacterial inactivation. Observed OH density by optical emission and absorption was proportional to the number of deactivated microorganism. Argon plasma jet in DI water also provided abundant OH on the interface of water and gas plasma. The OH radicals applied on porcine tooth sample selectively removed the stain without damaging the underlying enamel.
dc.format.mediumborn digital
dc.format.mediumdoctoral dissertations
dc.identifierChoi_colostate_0053A_11431.pdf
dc.identifierETDF2012500293ECEN
dc.identifier.urihttp://hdl.handle.net/10217/71552
dc.languageEnglish
dc.language.isoeng
dc.publisherColorado State University. Libraries
dc.relation.ispartof2000-2019
dc.rightsCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.
dc.subjectatmospheric pressure plasma
dc.subjectbacterial inactivation
dc.subjecthydroxyl
dc.subjectradio frequency
dc.subjecttissue ablation
dc.subjecttooth whitening
dc.titlePlasma chemical driven biomedical applications with a radio frequency driven atmospheric pressure plasma jet
dc.typeText
dcterms.rights.dplaThis Item is protected by copyright and/or related rights (https://rightsstatements.org/vocab/InC/1.0/). You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
thesis.degree.disciplineElectrical and Computer Engineering
thesis.degree.grantorColorado State University
thesis.degree.levelDoctoral
thesis.degree.nameDoctor of Philosophy (Ph.D.)

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