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Subcutaneous fat: a protector from metabolic dysregulation

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dc.contributor.authorBooth, Andrea, author
dc.contributor.authorMagnuson, Aaron, author
dc.contributor.authorFouts, Josephine, author
dc.contributor.authorBroeckling, Corey, author
dc.contributor.authorWei, Rosie, author
dc.contributor.authorWang, Dong, author
dc.contributor.authorPagliassotti, Michael, author
dc.contributor.authorFoster, Michelle, author
dc.date.accessioned2017-11-10T18:14:43Z
dc.date.available2017-11-10T18:14:43Z
dc.date.issued2017
dc.description.abstractLower body subcutaneous adipose tissue (LBSAT) is proposed to be a protective fat depot functioning as a “metabolic sink” for excess lipid accumulation. We have previously demonstrated that removal of this LBSAT in high fat diet (HFD) mice resulted in increased muscle triglycerides and was associated with decreased glucose tolerance. In the present study we removed varying amounts of SAT to comprehensively investigate mechanisms of the “metabolic sink” concept. Overall, accumulative fat removal worsens muscle insulin sensitivity and glucose tolerance. This decline may be related to lipid intermediates contained within the muscle.en_US
dc.format.mediumborn digital
dc.format.mediumStudent works
dc.format.mediumposters
dc.identifier.urihttps://hdl.handle.net/10217/184824
dc.languageEnglishen_US
dc.language.isoengen_US
dc.publisherColorado State University. Librariesen_US
dc.relation.ispartof2017 Projects
dc.rightsCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.
dc.subjectsubcutaneous adipose tissue
dc.subjectlipectomy
dc.subjectglucose intolerance
dc.subjectmuscle insulin resistance
dc.subjectmetabolic sink
dc.subjectmuscle lipids
dc.titleSubcutaneous fat: a protector from metabolic dysregulationen_US
dc.title.alternative047 - Andrea Deborah Booth-Kalajianen_US
dc.typeText
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