Mode of genetic inheritance modifies the association of head circumference and autism-related symptoms: a cross-sectional study
MetadataShow full item record
BACKGROUND: Frequently individuals with autism spectrum disorder (ASD) have been noted with a larger head circumberence (HC) than their typical developing peers. Bilogic hypotheses suggest that an overly rapid brain growth leads to the core symptoms of ASD by impairing connectivity. Literature is divided however where deleterious, protective and null associations of HC with ASD symptoms in individuals with ASD have been found. METHOD: Individuals (n = 1,416) from the Autism Genetic Resource with ASD were examined for associations of HC with ASD like symptoms. Mixed models controlling for sex, ...