Enhancing and Evaluating Global Pairwise Alignment of Protein-Protein Interaction Networks
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Network Alignment over graph-structured data has recently received considerable attention in many application domains. Global network alignment tries to uniquely find the best mapping for a node in one network to only one node in another network. The mapping is performed according to matching criteria that depend on the nature of the data. In molecular biology, functional orthologs, protein complexes, and evolutionarily conserved pathways are some examples of information uncovered by performing global network alignment. In this dissertation, we firstly survey the current techniques for global ...