MicroRNAs as a marker of cardiovascular disease in Marfan syndrome and Marfan-related disorders
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Genetic counseling is an important process in the care of patients with Marfan syndrome and related disorders (MSRD) because it provides individualized risk assessment that can aid in determining prognosis and help healthcare specialists optimize management. Marfan syndrome affects many body systems, but aortopathy, or disease of the aorta, is the most common cause of death. Currently, resources for predicting the prognosis for cardiovascular complications in Marfan syndrome are limited. However, in several human diseases, microRNAs (miRNAs) have emerged as a promising biomarker, or quantifiable ...