MERTK: a novel target in non-small cell lung cancer
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The American Cancer Society projects 221,200 new diagnoses and 158,040 deaths to occur in 2015 as a result of lung cancer. With a five-year relative survival rate that has only marginally improved from the 1970's (12%) to today (18%), new treatments are desperately needed for these large numbers of patients. Molecularly targeted therapies have begun to answer this call, with therapeutics against EGFR, ALK, and ROS1 now improving outcomes for patients with these specific genetic aberrations. However, the molecular events underlying lung cancer are complex, and many more therapeutic targets ...