Insights into the origins of functional mitral regurgitation and development of a corrective epicardial device
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Functional mitral regurgitation (FMR) is a frequent complication of left ventricular remodeling and carries a significant adverse prognosis. While significant progress has recently been made in the understanding of the pathophysiology and treatment of this disease, failure to obtain acceptable outcomes is driving researchers and clinicians to investigate alternative approaches to the consensual treatments. A thorough understanding of the normal anatomy and physiology of the mitral valve is warranted to underline the pathophysiological mechanisms of left ventricular remodeling leading to functional ...