On the role of circulating ATP in vascular control at rest and during exercise of aging humans
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The following investigation composes a series of experiments with the overall aim of determining the role for the circulating nucleotide adenosine triphosphate (ATP) in vascular control at rest and during exercise in humans of advanced age. We tested the general hypothesis that ATP has definite vasodilator and sympatholytic vasomotor properties in young adults during exercise, but that these actions are impaired in older adults; and that endogenously circulating levels of ATP are diminished during exercise in the aged population. Specifically, the experiments are outlined as such: 1) to determine ...