Vitamin C supplementation : a comparison of delivery methods and the ability to attenuate oxidative stress induced by ischemia-reperfusion
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Intravenous delivery of vitamin C to adult humans decreases indices of oxidative stress and in some instances improves physiological function. Oral delivery of vitamin C is more practical than intravenous but typically results in lower circulating vitamin C concentrations. The hypotheses for this study were, oral consumption of vitamin C encapsulated in liposomes would: 1) result in higher circulating vitamin C concentrations than a traditional oral supplement, and 2) better attenuate oxidative stress induced by ischemia-reperfusion. Eleven overweight/obese adults [age: 52±7 years; body mass ...